Mapping chromatin conformation
نویسنده
چکیده
Chromatin conformation capture (3C) and related techniques have become well-established methods to examine which distal DNA sequences are spatially located close to a locus of interest. Hi-C is a new addition to the growing set of 3C-based techniques that has extended the approach to a genome-wide analysis of nuclear chromatin using high-throughput DNA sequencing to generate global interaction maps for the entire genome.
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عنوان ژورنال:
دوره 2 شماره
صفحات -
تاریخ انتشار 2010